Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.67 |
| ▸ | TYR | P14679 | 1/20 | 0.67 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.67 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | ERN1 | O75460 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14613174 | 0.84 | ERN1 (0.67) | TRIM24TYRTRIM33CYP1A1CYP1B1 | |
| SCHEMBL18649676 | 0.82 | TYR (0.50) | TRIM24TYRTRIM33CYP1A1CYP1B1 | |
| SCHEMBL3210928 | 0.82 | TRIM24 (0.69) | TRIM24TYRTRIM33CYP1A1CYP1B1 | |
| SCHEMBL9065566 | 0.81 | CYP1A2 (0.52) | TRIM24TYRTRIM33CYP1A1CYP1B1 | |
| SCHEMBL30567454 | 0.81 | CYP1A2 (0.52) | TRIM24TYRTRIM33CYP1A1CYP1B1 | |
| SCHEMBL28351242 | 0.80 | MAPT (0.47) | TRIM24TYRTRIM33CYP1A1CYP1B1 | |
| SCHEMBL28348298 | 0.80 | TRIM24 (0.45) | TRIM24TYRTRIM33CYP1A1CYP1B1 | |
| SCHEMBL133876 | 0.80 | TYR (1.00) | TRIM24TYRTRIM33CYP1A1CYP1B1 | |
| SCHEMBL28351485 | 0.80 | TYR (0.48) | TRIM24TYRTRIM33CYP1A1CYP1B1 | |
| SCHEMBL10399237 | 0.80 | TRIM24 (0.67) | TRIM24TYRTRIM33CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140107166-A1 | HISTONE DEACETYLASE INHIBITORS AND METHODS OF USE THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2014-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107166-A1 | HISTONE DEACETYLASE INHIBITORS AND METHODS OF USE THEREOF | HDAC1, HDAC5, HDAC11 | TRIM24 2504/4885TYR 978/4885TRIM33 2111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.