Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1648513 | 0.91 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL1648748 | 0.89 | ROCK2 (0.83) | ROCK2ROCK1 | |
| SCHEMBL1647889 | 0.88 | ROCK2 (0.78) | ROCK2ROCK1 | |
| SCHEMBL1649563 | 0.86 | ROCK2 (0.80) | ROCK2ROCK1 | |
| SCHEMBL1648780 | 0.86 | ROCK2 (0.78) | ROCK2ROCK1 | |
| SCHEMBL1649783 | 0.85 | ROCK2 (0.81) | ROCK2ROCK1 | |
| SCHEMBL12779182 | 0.83 | ROCK2 (0.78) | ROCK2ROCK1 | |
| SCHEMBL12779346 | 0.83 | ROCK2 (0.80) | ROCK2ROCK1 | |
| SCHEMBL1648507 | 0.82 | ROCK2 (1.00) | ROCK2ROCK1 | |
| SCHEMBL1647891 | 0.81 | ROCK2 (1.00) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050245-A1 | BICYCLIC HETEROARYLS AS KINASE INHIBITORS | FENG YANGBO (US) | 2011-04-28 | — | — | WO | disclosed |
| WO-2011050245-A1 | BICYCLIC HETEROARYLS AS KINASE INHIBITORS | FENG YANGBO (US) | 2011-04-28 | — | — | WO | disclosed |