Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1649623 | 1.00 | ROCK1 (0.62) | ROCK1ROCK2 | |
| SCHEMBL1647787 | 1.00 | ROCK1 (0.62) | ROCK1ROCK2 | |
| SCHEMBL1648103 | 0.85 | ROCK1 (0.79) | ROCK1ROCK2 | |
| SCHEMBL1648105 | 0.80 | ROCK2 (0.83) | ROCK1ROCK2 | |
| SCHEMBL1647286 | 0.77 | ROCK1 (1.00) | ROCK1ROCK2 | |
| SCHEMBL1649568 | 0.77 | ROCK1 (1.00) | ROCK1ROCK2 | |
| SCHEMBL1649566 | 0.77 | ROCK1 (1.00) | ROCK1ROCK2 | |
| SCHEMBL1649581 | 0.77 | ROCK1 (1.00) | ROCK1ROCK2 | |
| SCHEMBL15968074 | 0.76 | ROCK2 (1.00) | ROCK1ROCK2 | |
| SCHEMBL15967948 | 0.76 | ROCK2 (1.00) | ROCK1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050245-A1 | BICYCLIC HETEROARYLS AS KINASE INHIBITORS | FENG YANGBO (US) | 2011-04-28 | — | — | WO | disclosed |
| WO-2011050245-A1 | BICYCLIC HETEROARYLS AS KINASE INHIBITORS | FENG YANGBO (US) | 2011-04-28 | — | — | WO | disclosed |