Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 7/20 | 0.35 |
| ▸ | CTSS | P25774 | 7/20 | 0.35 |
| ▸ | CTSL | P07711 | 5/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | CCR7 | P32248 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16478113 | 0.88 | CTSL (0.35) | CTSBCTSSCTSLCCR7CCR6 | |
| SCHEMBL16478087 | 0.76 | CTSC (0.51) | CTSK | |
| SCHEMBL16485766 | 0.66 | CTSC (0.46) | CTSSCTSK | |
| SCHEMBL16485783 | 0.66 | CTSC (0.68) | CTSK | |
| Trifluoroacetic Acid SCHEMBL16478192 | 0.64 | CTSC (0.61) | CTSBCTSLCTSK | |
| SCHEMBL27772527 | 0.63 | MKNK1 (0.51) | MYC | |
| SCHEMBL29735324 | 0.60 | PLAU (0.54) | MYCUSP30 | |
| SCHEMBL2935534 | 0.60 | PLAU (0.54) | MYCUSP30 | |
| Hydrochloric Acid SCHEMBL9792812 | 0.60 | MKNK1 (0.52) | MYC | |
| SCHEMBL7229397 | 0.60 | MKNK1 (0.58) | MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011154677-A1 | SUBSTITUTED N-[1-CYANO-2-(PHENYL)ETHYL] 1-AMINOCYCLOALK-1-YLCARBOXAMIDE COMPOUNDS - 760 | ASTRAZENECA AB (SE) | 2011-12-15 | — | — | WO | disclosed |