Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 13/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16478097 | 0.87 | CTSC (0.48) | CTSCKCNH2 | |
| SCHEMBL3653385 | 0.78 | CTSC (0.55) | CTSCKCNH2 | |
| SCHEMBL16478127 | 0.78 | CTSC (0.49) | CTSCKCNH2TSPO | |
| SCHEMBL290463 | 0.78 | CTSC (0.49) | CTSCKCNH2ASAH1MAPT | |
| SCHEMBL16478115 | 0.77 | CTSC (0.49) | CTSCKCNH2ASAH1 | |
| SCHEMBL3656287 | 0.76 | CTSC (0.48) | CTSCKCNH2LMNANPSR1 | |
| SCHEMBL290107 | 0.73 | CTSC (0.49) | CTSCKCNH2TSPO | |
| SCHEMBL16478103 | 0.72 | CTSC (0.41) | CTSCNPSR1 | |
| SCHEMBL3687606 | 0.71 | CTSC (0.72) | CTSCKCNH2 | |
| SCHEMBL16478221 | 0.71 | CTSC (0.38) | CTSCKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011154677-A1 | SUBSTITUTED N-[1-CYANO-2-(PHENYL)ETHYL] 1-AMINOCYCLOALK-1-YLCARBOXAMIDE COMPOUNDS - 760 | ASTRAZENECA AB (SE) | 2011-12-15 | — | — | WO | disclosed |