Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 17/20 | 0.60 |
| ▸ | MET | P08581 | 2/20 | 0.54 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.51 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10322501 | 0.90 | LRRK2 (0.64) | LRRK2METSGMS2 | |
| SCHEMBL10322888 | 0.90 | LRRK2 (0.64) | LRRK2METSGMS2 | |
| SCHEMBL10322891 | 0.88 | LRRK2 (0.68) | LRRK2METSGMS2 | |
| SCHEMBL10321935 | 0.88 | LRRK2 (0.68) | LRRK2METSGMS2 | |
| SCHEMBL2895175 | 0.78 | PRMT5 (0.56) | — | |
| SCHEMBL4314170 | 0.78 | PRMT5 (0.56) | — | |
| SCHEMBL4314700 | 0.78 | PRMT5 (0.56) | — | |
| SCHEMBL1648747 | 0.78 | LRRK2 (0.66) | LRRK2METSGMS2 | |
| SCHEMBL6917993 | 0.78 | LRRK2 (0.66) | LRRK2METSGMS2 | |
| SCHEMBL1648751 | 0.78 | LRRK2 (0.66) | LRRK2METSGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011038572-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-04-07 | — | — | WO | disclosed |