Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 6/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4280004 | 0.83 | CACNA1I (0.44) | KDM1ACACNA1ICYP2D6CACNA1HKCNH2 | |
| SCHEMBL4275652 | 0.73 | CACNA1I (0.67) | CACNA1ICYP2D6CACNA1HKCNH2 | |
| SCHEMBL22019051 | 0.72 | NPC1 (0.42) | KDM1ACACNA1ICYP2D6CACNA1HKCNH2 | |
| SCHEMBL19112809 | 0.71 | KDM1A (0.44) | KDM1ANPY5RKCNH2ALDH1A1HTR4 | |
| SCHEMBL4274395 | 0.71 | CACNA1I (0.58) | CACNA1ICYP2D6CACNA1HKCNH2 | |
| SCHEMBL19113009 | 0.71 | KCNH2 (0.41) | KDM1ACACNA1ICYP2D6CACNA1HKCNH2 | |
| SCHEMBL1428801 | 0.70 | KDM1A (0.46) | KDM1ACACNA1ICYP2D6CACNA1HKCNH2 | |
| SCHEMBL4278285 | 0.70 | CACNA1I (0.66) | HTR7CACNA1ICYP2D6CACNA1HKCNH2 | |
| SCHEMBL4271000 | 0.69 | CACNA1I (0.59) | HTR7CACNA1ICYP2D6CACNA1HKCNH2 | |
| SCHEMBL4271496 | 0.69 | KCNH2 (0.50) | CACNA1ICYP2D6CACNA1HKCNH2HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140011996-A1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | ZALICUS PHARMACEUTICALS LTD. (CA) | 2014-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140011996-A1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | CACNA1G, CACNA1H, CACNA1B | KDM1A 3578/4885CXCR4 3881/4885NPY5R 3409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.