Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 12/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3500708 | 0.86 | KDM4E (0.67) | KDM4EPOLBGAAGABRA2GABRB2 | |
| SCHEMBL1445451 | 0.86 | KDM4E (1.00) | KDM4EPOLBGAAALDH1A1HPGD | |
| SCHEMBL7269185 | 0.85 | KDM4E (0.78) | KDM4EPOLBGAAGABRA2GABRB2 | |
| SCHEMBL17437886 | 0.85 | KDM4E (0.78) | KDM4EPOLBGAAGABRA2GABRB2 | |
| SCHEMBL20887367 | 0.84 | KDM4E (0.72) | KDM4EPOLBGAAGABRA2GABRB2 | |
| SCHEMBL975342 | 0.84 | KDM4E (0.76) | KDM4EPOLBGAAGABRA2GABRB2 | |
| SCHEMBL15767159 | 0.84 | KDM4E (0.76) | KDM4EPOLBGAAGABRA2GABRB2 | |
| SCHEMBL16691126 | 0.84 | KDM4E (0.76) | KDM4EPOLBGAAGABRA2GABRB2 | |
| SCHEMBL22148188 | 0.83 | KDM4E (0.74) | KDM4EPOLBGAAGABRA2GABRB2 | |
| SCHEMBL15744771 | 0.83 | KDM4E (0.74) | KDM4EPOLBGAAGABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651934-B1 | IMIDAZOPYRIDINES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN SCIENCES IRELAND UC (IE) | 2017-02-22 | — | — | EP | disclosed |
| US-8846672-B2 | Imidazopyridines as respiratory syncytial virus antiviral agents | JANSSEN R&D IRELAND (IE) | 2014-09-30 | — | — | US | disclosed |
| US-8846672-B2 | Imidazopyridines as respiratory syncytial virus antiviral agents | JANSSEN R&D IRELAND (IE) | 2014-09-30 | — | — | US | disclosed |
| EP-2651934-A1 | IMIDAZOPYRIDINES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | Janssen R&D Ireland (IE) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080451-A1 | IMIDAZOPYRIDINES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN R&D IRELAND (IE) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012080451-A1 | IMIDAZOPYRIDINES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN R&D IRELAND (IE) | 2012-06-21 | — | — | WO | disclosed |
| WO-2011050245-A1 | BICYCLIC HETEROARYLS AS KINASE INHIBITORS | FENG YANGBO (US) | 2011-04-28 | — | — | WO | disclosed |
| WO-2011050245-A1 | BICYCLIC HETEROARYLS AS KINASE INHIBITORS | FENG YANGBO (US) | 2011-04-28 | — | — | WO | disclosed |