Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16480468 | 1.00 | SMN1; SMN2 (0.58) | SMN1; SMN2POLBLMNAMAPTMEN1 | |
| SCHEMBL9893033 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2POLBLMNAMAPTMEN1 | |
| SCHEMBL9893045 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2POLBLMNAMAPTMEN1 | |
| SCHEMBL9891827 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2POLBLMNAMAPTMEN1 | |
| SCHEMBL9891886 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2POLBLMNAMAPTMEN1 | |
| SCHEMBL9103651 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2POLBLMNAMAPTMEN1 | |
| SCHEMBL3707377 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2POLBLMNAMAPTMEN1 | |
| SCHEMBL3707374 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2POLBLMNAMAPTMEN1 | |
| SCHEMBL22187889 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBLMNAMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL28597259 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2POLBLMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |