Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9893033 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2ATDP1POLB | |
| SCHEMBL16480375 | 0.85 | SMN1; SMN2 (0.58) | SMN1; SMN2MEN1KMT2ATDP1POLB | |
| SCHEMBL16480468 | 0.85 | SMN1; SMN2 (0.58) | SMN1; SMN2MEN1KMT2ATDP1POLB | |
| SCHEMBL9891886 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2ATDP1POLB | |
| SCHEMBL9891827 | 0.83 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2ATDP1POLB | |
| SCHEMBL9103651 | 0.80 | SMN1; SMN2 (0.64) | SMN1; SMN2MEN1KMT2APOLBLMNA | |
| SCHEMBL3707374 | 0.80 | SMN1; SMN2 (0.64) | SMN1; SMN2MEN1KMT2APOLBLMNA | |
| SCHEMBL3707377 | 0.80 | SMN1; SMN2 (0.64) | SMN1; SMN2MEN1KMT2APOLBLMNA | |
| SCHEMBL9892995 | 0.79 | CNR1 (0.50) | SMN1; SMN2MEN1KMT2ATDP1POLB | |
| SCHEMBL22187891 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2ATDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | SMN1; SMN2 4659/4885MEN1 4874/4885KMT2A 3551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.