Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28804472 | 0.85 | PARP1 (0.49) | MEN1KMT2ARAB9AALDH1A1L3MBTL1 | |
| SCHEMBL16542508 | 0.85 | ALDH1A1 (0.54) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2570464 | 0.85 | MEN1 (0.55) | MEN1KMT2AHDAC8HDAC6RAB9A | |
| SCHEMBL2570466 | 0.85 | MEN1 (0.55) | MEN1KMT2AHDAC8HDAC6RAB9A | |
| SCHEMBL16480486 | 0.84 | GAA (0.53) | KMT2ARAB9ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL9893047 | 0.84 | MEN1 (0.54) | MEN1KMT2AHDAC8HDAC6RAB9A | |
| SCHEMBL9891741 | 0.84 | MEN1 (0.54) | MEN1KMT2AHDAC8HDAC6RAB9A | |
| SCHEMBL16480487 | 0.83 | HDAC2 (0.46) | MEN1KMT2AHDAC8HDAC6RAB9A | |
| SCHEMBL16480488 | 0.82 | PMM2 (0.45) | MEN1KMT2ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL16480394 | 0.76 | KMT2A (0.48) | MEN1KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |