Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23183278 | 0.94 | LMNA (0.43) | LMNAHRH3 | |
| SCHEMBL18212487 | 0.81 | LMNA (0.44) | LMNAHRH3 | |
| SCHEMBL16438632 | 0.81 | LMNA (0.44) | LMNAHRH3 | |
| SCHEMBL14370057 | 0.81 | LMNA (0.44) | LMNAHRH3 | |
| SCHEMBL18638053 | 0.80 | LMNA (0.37) | LMNAHRH3KCNH2 | |
| SCHEMBL24180422 | 0.80 | LMNA (0.37) | LMNAHRH3KCNH2 | |
| SCHEMBL9892991 | 0.78 | HTT (0.37) | HRH3 | |
| SCHEMBL21009044 | 0.78 | HTT (0.34) | — | |
| SCHEMBL24180425 | 0.78 | MEN1 (0.44) | LMNAHRH3KCNH2 | |
| SCHEMBL10902326 | 0.78 | LMNA (0.49) | LMNAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |