Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.34 |
| ▸ | NT5E | P21589 | 3/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.33 |
| ▸ | HINT1 | P49773 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.31 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16480878 | 0.92 | ADORA2A (0.40) | ADORA2ANT5ESLC29A1HINT1ADORA1 | |
| SCHEMBL16480819 | 0.86 | HINT1 (0.41) | NT5EHINT1ADORA3 | |
| SCHEMBL16480789 | 0.86 | ADORA2A (0.46) | ADORA2ASLC29A1ADORA2BADORA1ADORA3 | |
| SCHEMBL16480500 | 0.82 | NT5E (0.36) | ADORA2ANT5ESLC29A1ADORA2BADORA1 | |
| SCHEMBL16480519 | 0.82 | NT5E (0.36) | ADORA2ANT5ESLC29A1ADORA2BADORA1 | |
| SCHEMBL16480518 | 0.82 | NT5E (0.36) | ADORA2ANT5ESLC29A1ADORA2BADORA1 | |
| SCHEMBL19863222 | 0.82 | ADORA2A (0.40) | ADORA2ANT5EHINT1ADORA2BADORA1 | |
| SCHEMBL16368444 | 0.82 | ADORA2A (0.40) | ADORA2ANT5EHINT1ADORA2BADORA1 | |
| SCHEMBL16480904 | 0.82 | CYP3A4 (0.36) | NT5EHINT1 | |
| SCHEMBL17615301 | 0.82 | CYP3A4 (0.36) | NT5EHINT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014058801-A1 | 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION | IDENIX PHARMACEUTICALS, INC. (US) | 2014-04-17 | — | — | WO | disclosed |