Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15022978 | 0.91 | ACACB (0.52) | ACACB | |
| SCHEMBL6326158 | 0.79 | GFER (0.40) | ACACB | |
| SCHEMBL3178582 | 0.79 | NPY5R (0.40) | ACACB | |
| SCHEMBL12408720 | 0.79 | GPR119 (0.49) | — | |
| SCHEMBL25364252 | 0.78 | NOTUM (0.47) | ACACB | |
| SCHEMBL16464504 | 0.76 | ACACB (0.47) | ACACB | |
| SCHEMBL16464506 | 0.76 | ACACB (0.47) | ACACB | |
| SCHEMBL2126451 | 0.74 | MAPT (0.51) | — | |
| SCHEMBL6161538 | 0.74 | MAPT (0.51) | — | |
| SCHEMBL16481347 | 0.74 | ACACB (0.71) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169205-B2 | Pyrrolidine derivatives, pharmaceutical compositions and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-10-27 | — | — | US | disclosed |
| US-9169205-B2 | Pyrrolidine derivatives, pharmaceutical compositions and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-10-27 | — | — | US | disclosed |
| WO-2014056771-A1 | NEW PYRROLIDINE DERIVATIVES AND THEIR USE AS ACETYL-COA CARBOXYLASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-04-17 | — | — | WO | disclosed |