SCHEMBL16482162

SCHEMBL16482162

c1ccc(N(c2ccccc2)c2ccc3oc4c(ccc5c4c4cc(-n6c7ccccc7c7ccccc76)ccc4n5-c4ccccc4)c3c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.35
POLB P06746 1/20 0.35
TSHR P16473 1/20 0.35
BRCA1 P38398 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 1/20 0.35
JAK2 O60674 1/20 0.31
JAK3 P52333 1/20 0.31
CA12 O43570 1/20 0.30
CA9 Q16790 1/20 0.30
PPARG P37231 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
NR2E3 Q9Y5X4 1/20 0.30
NCOR2 Q9Y618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17426284 0.94 MEN1 (0.35) KDM4EATML3MBTL1ALDH1A1MEN1
SCHEMBL16773267 0.93 JAK2 (0.32) KDM4EATML3MBTL1ALDH1A1MEN1
SCHEMBL17426323 0.93 KDM4E (0.35) KDM4EATML3MBTL1ALDH1A1MEN1
SCHEMBL17426316 0.93 MEN1 (0.34) KDM4EATML3MBTL1ALDH1A1MEN1
SCHEMBL11933055 0.92 KDM4E (0.41) KDM4EATML3MBTL1ALDH1A1MEN1
SCHEMBL26430761 0.91 KDM4E (0.37) KDM4EATML3MBTL1ALDH1A1MEN1
SCHEMBL17426405 0.91 MEN1 (0.32) KDM4EATML3MBTL1ALDH1A1MEN1
SCHEMBL17426318 0.91 KDM4E (0.40) KDM4EATML3MBTL1ALDH1A1MEN1
SCHEMBL17426315 0.91 MEN1 (0.32) KDM4EALDH1A1MEN1POLBTSHR
SCHEMBL31764 0.90 KDM4E (0.39) KDM4EATML3MBTL1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014057659-A1 COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT PRODUCED USING SAME 出光興産株式会社 (JP) 2014-04-17 WO disclosed