SCHEMBL16773267

SCHEMBL16773267

c1ccc(N(c2ccccc2)c2ccc(-n3c4ccc(N(c5ccccc5)c5ccccc5)cc4c4c5oc6ccc(N(c7ccccc7)c7ccccc7)cc6c5ccc43)cc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
JAK2 O60674 1/20 0.32
JAK3 P52333 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
TSHR P16473 1/20 0.32
BRCA1 P38398 1/20 0.32
KMT2A Q03164 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16773309 0.94 ALDH1A1 (0.34) JAK2JAK3MEN1ALDH1A1POLB
SCHEMBL16482162 0.93 KDM4E (0.38) JAK2JAK3MEN1ALDH1A1POLB
SCHEMBL23597939 0.91 PLA2G2A (0.32) JAK2JAK3MEN1ALDH1A1POLB
SCHEMBL26430761 0.91 KDM4E (0.37) JAK2JAK3MEN1ALDH1A1POLB
SCHEMBL16773310 0.91 ALOX5 (0.33) JAK2JAK3MEN1ALDH1A1POLB
SCHEMBL11933043 0.90 KDM4E (0.38) JAK2JAK3MEN1ALDH1A1POLB
SCHEMBL15582951 0.90 ALOX5 (0.32) MEN1ALDH1A1POLBTSHRBRCA1
SCHEMBL15582802 0.90 ALOX5 (0.32) MEN1ALDH1A1POLBTSHRBRCA1
SCHEMBL17426284 0.89 MEN1 (0.35) MEN1ALDH1A1POLBTSHRBRCA1
SCHEMBL16437680 0.89 ALDH1A1 (0.34) JAK2JAK3MEN1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150155498-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE CONTAINING THE SAME ROHM & HAAS ELECT MAT (KR) 2015-06-04 US disclosed
US-20150155498-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE CONTAINING THE SAME ROHM & HAAS ELECT MAT (KR) 2015-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150155498-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE CONTAINING THE SAME OCIAD2, OCIAD1, OR10J3 JAK2 4857/4885JAK3 4736/4885MEN1 3270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.