SCHEMBL16482193

SCHEMBL16482193

c1ccc2c(c1)sc1c(-c3ccc(-n4c5ccc6c7ccccc7sc6c5c5cccc(-n6c7ccccc7c7ccccc76)c54)cc3)cccc12

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.42
PRKDC P78527 2/20 0.37
PARP14 Q460N5 1/20 0.33
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TNKS O95271 1/20 0.30
TNKS2 Q9H2K2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16482334 0.92 TNKS (0.35) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL16482140 0.92 KDM4E (0.37) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL16482393 0.90 ATM (0.41) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL16482137 0.89 KDM4E (0.35) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL16482158 0.89 ALOX5 (0.43) ALOX5PRKDCPARP14TNKSTNKS2
SCHEMBL16482497 0.89 TNKS (0.36) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL16482494 0.89 TNKS (0.36) ALOX5PRKDCKDM4EATML3MBTL1
SCHEMBL16482294 0.89 ALOX5 (0.38) ALOX5PRKDCPARP14KDM4EATM
SCHEMBL16482348 0.89 PRKDC (0.36) ALOX5PRKDC
SCHEMBL15137578 0.89 ALOX5 (0.47) ALOX5PRKDCPARP14KDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014057659-A1 COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT PRODUCED USING SAME 出光興産株式会社 (JP) 2014-04-17 WO disclosed