Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.34 |
| ▸ | FABP7 | O15540 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31437117 | 0.91 | ITGB3 (0.45) | ITGB3ITGA2BPTPN1PPARGPPARA | |
| SCHEMBL17265629 | 0.91 | ITGB3 (0.45) | ITGB3ITGA2BPTPN1PPARGPPARA | |
| SCHEMBL15632803 | 0.91 | ITGB3 (0.45) | ITGB3ITGA2BPTPN1PPARGPPARA | |
| SCHEMBL31037195 | 0.91 | ITGB3 (0.45) | ITGB3ITGA2BPTPN1PPARGPPARA | |
| SCHEMBL31037194 | 0.91 | ITGB3 (0.45) | ITGB3ITGA2BPTPN1PPARGPPARA | |
| SCHEMBL25185647 | 0.82 | ITGB3 (0.45) | ITGB3ITGA2BPTPN1PPARGPPARA | |
| SCHEMBL29633748 | 0.82 | FABP5 (0.37) | ITGB3ITGA2BPPARGPPARAFABP5 | |
| SCHEMBL25185646 | 0.82 | ITGB3 (0.45) | ITGB3ITGA2BPTPN1PPARGPPARA | |
| SCHEMBL29855055 | 0.82 | ITGB3 (0.45) | ITGB3ITGA2BPTPN1PPARGPPARA | |
| SCHEMBL16482913 | 0.82 | PTPN1 (0.42) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057418-A2 | SOLUTION PHASE PROCESSES FOR THE MANUFACTURE OF MACROCYCLIC DEPSIPEPTIDES AND NEW INTERMEDIATES | NOVARTIS AG (CH) | 2014-04-17 | — | — | WO | disclosed |