Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.45 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483463 | 0.94 | MEN1 (0.45) | MEN1KMT2AHSP90AA1MAPTESR1 | |
| SCHEMBL10041759 | 0.90 | ESR1 (0.51) | MEN1KMT2AHSP90AA1MAPTESR1 | |
| SCHEMBL9976950 | 0.90 | ESR2 (0.60) | MEN1KMT2AHSP90AA1MAPTESR1 | |
| SCHEMBL15803069 | 0.88 | ESR1 (0.48) | MEN1KMT2AHSP90AA1MAPTESR1 | |
| SCHEMBL16484845 | 0.87 | RECQL (0.44) | MEN1KMT2AHSP90AA1MAPTESR1 | |
| SCHEMBL19818255 | 0.87 | ESR1 (0.48) | MEN1KMT2AHSP90AA1MAPTESR1 | |
| SCHEMBL9976944 | 0.87 | ESR1 (0.56) | MEN1KMT2AHSP90AA1MAPTESR1 | |
| SCHEMBL12912523 | 0.86 | ESR2 (0.52) | MEN1KMT2AHSP90AA1MAPTESR1 | |
| SCHEMBL15803043 | 0.86 | ESR1 (0.47) | MEN1KMT2AHSP90AA1MAPTESR1 | |
| SCHEMBL9976949 | 0.86 | ESR1 (0.55) | MEN1KMT2AHSP90AA1MAPTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |