Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.39 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 2/20 | 0.39 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483051 | 0.94 | MEN1 (0.49) | MEN1KMT2AHSP90AA1MAPTRECQL | |
| SCHEMBL16484845 | 0.93 | RECQL (0.44) | MEN1KMT2AHSP90AA1MAPTRECQL | |
| SCHEMBL16483382 | 0.91 | MEN1 (0.42) | MEN1KMT2AHSP90AA1MAPTRECQL | |
| SCHEMBL11954062 | 0.88 | RECQL (0.47) | RECQLESR2ESR1MAPK1HTT | |
| SCHEMBL12611887 | 0.87 | RECQL (0.46) | RECQLESR2ESR1MAPK1HTT | |
| SCHEMBL15803041 | 0.86 | RECQL (0.45) | MEN1KMT2AMAPTRECQLESR2 | |
| SCHEMBL15803069 | 0.85 | ESR1 (0.48) | MEN1KMT2AHSP90AA1MAPTRECQL | |
| SCHEMBL16484865 | 0.84 | RECQL (0.48) | MEN1KMT2ARECQLESR2ESR1 | |
| SCHEMBL10041759 | 0.84 | ESR1 (0.51) | MEN1KMT2AHSP90AA1MAPTRECQL | |
| SCHEMBL15803162 | 0.84 | ESR1 (0.46) | MEN1KMT2AHSP90AA1MAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |