Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | CCNC | P24863 | 2/20 | 0.39 |
| ▸ | CDK8 | P49336 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483076 | 0.95 | POLB (0.46) | POLBNPC1RAB9AIKBKETBK1 | |
| SCHEMBL16483101 | 0.94 | POLB (0.48) | POLBNPC1RAB9AIKBKETBK1 | |
| SCHEMBL16483626 | 0.92 | IKBKE (0.44) | POLBNPC1RAB9AIKBKETBK1 | |
| SCHEMBL16483470 | 0.87 | IKBKE (0.49) | IKBKETBK1DYRK1APIK3CAERN1 | |
| SCHEMBL16483068 | 0.87 | IKBKE (0.49) | IKBKETBK1DYRK1APIK3CAERN1 | |
| SCHEMBL16483069 | 0.87 | IKBKE (0.43) | IKBKETBK1PIK3CACCNCCDK8 | |
| SCHEMBL16484799 | 0.86 | NPC1 (0.49) | POLBNPC1RAB9ADYRK1APIK3CA | |
| SCHEMBL16483499 | 0.86 | POLB (0.51) | POLBNPC1RAB9ADYRK1ATP53 | |
| SCHEMBL16483771 | 0.86 | POLB (0.51) | POLBNPC1RAB9ADYRK1ATP53 | |
| SCHEMBL16483270 | 0.86 | NPC1 (0.51) | POLBNPC1RAB9ADYRK1APIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |