Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 2/20 | 0.39 |
| ▸ | CDK8 | P49336 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483083 | 0.94 | POLB (0.47) | POLBNPC1RAB9AIKBKETBK1 | |
| SCHEMBL16483076 | 0.92 | POLB (0.46) | POLBNPC1RAB9AIKBKETBK1 | |
| SCHEMBL16483102 | 0.89 | NPC1 (0.48) | POLBNPC1RAB9APIK3CADYRK1A | |
| SCHEMBL16483420 | 0.87 | NPC1 (0.57) | POLBNPC1RAB9APIK3CADYRK1A | |
| SCHEMBL13682493 | 0.87 | POLB (0.60) | POLBNPC1RAB9APIK3CADYRK1A | |
| SCHEMBL16483626 | 0.86 | IKBKE (0.44) | POLBNPC1RAB9AIKBKETBK1 | |
| SCHEMBL16483498 | 0.86 | TNF (0.51) | POLBNPC1RAB9APIK3CADYRK1A | |
| SCHEMBL16483453 | 0.86 | NPC1 (0.53) | POLBNPC1RAB9APIK3CADYRK1A | |
| SCHEMBL16483642 | 0.86 | POLB (0.53) | POLBNPC1RAB9APIK3CADYRK1A | |
| SCHEMBL16483536 | 0.85 | POLB (0.62) | POLBNPC1RAB9APIK3CADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |