Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 2/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483461 | 0.88 | CYP11B1 (0.49) | PRKCZCYP11B1CYP11B2CYP3A4CYP1A2 | |
| SCHEMBL16483100 | 0.87 | PDGFRB (0.54) | PDGFRBPDGFRAPIK3CDPIK3CACYP2A6 | |
| SCHEMBL20873082 | 0.87 | PDGFRB (0.57) | PRKCZCYP11B1CYP11B2CYP3A4CYP1A2 | |
| SCHEMBL15497847 | 0.87 | PDGFRB (0.54) | CYP1A2PDGFRBPDGFRAPIK3CDPIK3CA | |
| SCHEMBL16483078 | 0.84 | CYP11B1 (0.48) | PRKCZCYP11B1CYP11B2CYP3A4CYP1A2 | |
| SCHEMBL17322716 | 0.84 | PDGFRB (0.49) | PDGFRBPDGFRAPIK3CDPIK3CACYP2A6 | |
| SCHEMBL15497834 | 0.84 | PDGFRB (0.51) | CYP1A2PDGFRBPDGFRAPIK3CDPIK3CA | |
| SCHEMBL16483102 | 0.83 | NPC1 (0.48) | PRKCZCYP11B1CYP11B2CYP3A4CYP1A2 | |
| SCHEMBL19768478 | 0.83 | ERN1 (0.39) | PRKCZCYP11B1CYP11B2CYP3A4CYP1A2 | |
| SCHEMBL19768529 | 0.82 | PDGFRB (0.40) | PRKCZCYP11B1CYP11B2CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |