Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483461 | 0.93 | CYP11B1 (0.49) | NPC1POLBRAB9APRKCZCYP11B1 | |
| SCHEMBL16483078 | 0.90 | CYP11B1 (0.48) | NPC1POLBRAB9APRKCZCYP11B1 | |
| SCHEMBL16483101 | 0.89 | POLB (0.48) | NPC1POLBRAB9ADYRK1AERN1 | |
| SCHEMBL16483536 | 0.85 | POLB (0.62) | NPC1POLBRAB9ACYP3A4DYRK1A | |
| SCHEMBL16483086 | 0.84 | NPC1 (0.54) | NPC1POLBRAB9ADYRK1APIK3CA | |
| SCHEMBL16483088 | 0.84 | NPC1 (0.54) | NPC1POLBRAB9ACYP3A4DYRK1A | |
| SCHEMBL16483420 | 0.84 | NPC1 (0.57) | NPC1POLBRAB9ADYRK1APIK3CA | |
| SCHEMBL13682493 | 0.84 | POLB (0.60) | NPC1POLBRAB9ACYP3A4DYRK1A | |
| SCHEMBL16483534 | 0.84 | PRKCZ (0.47) | PRKCZCYP11B1CYP11B2CYP3A4CYP1A2 | |
| SCHEMBL16483453 | 0.83 | NPC1 (0.53) | NPC1POLBRAB9ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |