Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483167 | 0.92 | TNF (0.37) | TNFALOX5MAPK14PIK3CDPIK3CB | |
| SCHEMBL16483496 | 0.92 | TNF (0.44) | TNFALOX5MEN1HSP90AA1MAPT | |
| SCHEMBL16484935 | 0.90 | TNF (0.42) | TNFALOX5MEN1HSP90AA1MAPT | |
| SCHEMBL16483317 | 0.90 | TNF (0.44) | TNFMAPK14PIK3CDPIK3CBPIK3CG | |
| SCHEMBL16483174 | 0.87 | TNF (0.45) | TNFALOX5MAPK14PIK3CDPIK3CB | |
| SCHEMBL16483422 | 0.87 | TNF (0.42) | TNFALOX5MAPK14CYP17A1CYP1A2 | |
| SCHEMBL16483423 | 0.85 | TNF (0.39) | TNFMAPK14CYP17A1CYP1A2 | |
| SCHEMBL16484857 | 0.85 | TNF (0.39) | TNFALOX5MAPK14CYP17A1CYP1A2 | |
| SCHEMBL16483454 | 0.85 | TNF (0.44) | TNFALOX5MAPK14CYP17A1CYP1A2 | |
| SCHEMBL16483509 | 0.84 | TNF (0.38) | TNFALOX5HASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |