Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16484935 | 0.92 | TNF (0.42) | TNFMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL16483151 | 0.92 | TNF (0.44) | TNFMAPTALOX5MEN1HSP90AA1 | |
| SCHEMBL16483167 | 0.90 | TNF (0.37) | TNFMAPTALOX5MEN1HSP90AA1 | |
| SCHEMBL16483509 | 0.90 | TNF (0.38) | TNFALOX5 | |
| SCHEMBL16483407 | 0.90 | TNF (0.44) | TNFMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL16483454 | 0.89 | TNF (0.44) | TNFMAPTKDM4ECDC7CDK2 | |
| SCHEMBL16483430 | 0.87 | TNF (0.45) | TNFMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL16483423 | 0.87 | TNF (0.39) | TNFCDC7CDK2 | |
| SCHEMBL16483422 | 0.87 | TNF (0.42) | TNFKDM4ECDC7CDK2ALOX5 | |
| SCHEMBL16483456 | 0.86 | TNF (0.36) | TNFMAPTALDH1A1CDC7CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |