Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 12/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 11/20 | 0.54 |
| ▸ | CYP17A1 | P05093 | 7/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483072 | 1.00 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP17A1CYP19A1PGR | |
| SCHEMBL16483670 | 0.98 | CYP11B1 (0.52) | CYP11B1CYP11B2CYP17A1CYP19A1PGR | |
| SCHEMBL16484804 | 0.95 | CYP11B1 (0.49) | CYP11B1CYP11B2CYP17A1CYP19A1PGR | |
| SCHEMBL16483085 | 0.94 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP17A1CYP19A1PGR | |
| SCHEMBL16483691 | 0.93 | PIK3CA (0.48) | CYP11B1CYP11B2CYP17A1CYP19A1PGR | |
| SCHEMBL16483398 | 0.93 | CYP11B1 (0.50) | CYP11B1CYP11B2CYP17A1CYP19A1PGR | |
| SCHEMBL16483227 | 0.93 | CYP11B2 (0.58) | CYP11B1CYP11B2CYP17A1CYP19A1PGR | |
| SCHEMBL16483043 | 0.93 | CYP11B1 (0.50) | CYP11B1CYP11B2CYP17A1CYP19A1PGR | |
| SCHEMBL16483338 | 0.93 | PIK3CA (0.53) | CYP11B1CYP11B2CYP17A1CYP19A1PGR | |
| SCHEMBL16483784 | 0.92 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP17A1CYP19A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |