Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | CCR8 | P51685 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483436 | 0.93 | POLB (0.50) | POLBNPC1RAB9ADYRK1ALMNA | |
| SCHEMBL13682493 | 0.90 | POLB (0.60) | POLBNPC1RAB9ADYRK1ALMNA | |
| SCHEMBL16483435 | 0.90 | PDGFRB (0.46) | POLBNPC1RAB9ALMNATP53 | |
| SCHEMBL16483642 | 0.89 | POLB (0.53) | POLBNPC1RAB9ADYRK1ALMNA | |
| SCHEMBL16483484 | 0.89 | POLB (0.49) | POLBNPC1RAB9ADYRK1ALMNA | |
| SCHEMBL16483536 | 0.88 | POLB (0.62) | POLBNPC1RAB9ADYRK1ALMNA | |
| SCHEMBL16483098 | 0.88 | POLB (0.54) | POLBNPC1RAB9ADYRK1ALMNA | |
| SCHEMBL13682530 | 0.87 | POLB (0.57) | POLBNPC1RAB9ADYRK1ATP53 | |
| SCHEMBL16483535 | 0.87 | LMNA (0.48) | LMNATP53MMP2PSMD14SMN1; SMN2 | |
| SCHEMBL16483434 | 0.86 | LMNA (0.49) | LMNATP53MMP2SMN1; SMN2CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |