Sugi Predict

Sugi Predict / Compounds / SCHEMBL16484353

SCHEMBL16484353

SCHEMBL16484353

c1ccc(-n2c3ccccc3c3cc(-n4c5ccccc5c5c6oc7c(ccc8c7c7ccccc7n8-c7cc(-c8ccc9oc%10ccccc%10c9c8)cc(-c8ccc9oc%10ccccc%10c9c8)c7)c6ccc54)ccc32)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.37
▸ ATM Q13315 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ MEN1 O00255 2/20 0.34
▸ ALDH1A1 P00352 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ POLB P06746 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ BRCA1 P38398 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ PLA2G2A P14555 2/20 0.34
▸ PLA2G4A P47712 2/20 0.34
▸ PLA2G10 O15496 1/20 0.34
▸ NPC1 O15118 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ EDNRB P24530 1/20 0.30
▸ EDNRA P25101 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16484374 0.97 KDM4E (0.39) KDM4EATML3MBTL1MEN1ALDH1A1
SCHEMBL16484380 0.96 KDM4E (0.37) KDM4EATML3MBTL1MEN1ALDH1A1
SCHEMBL16483914 0.96 KDM4E (0.38) KDM4EATML3MBTL1MEN1ALDH1A1
SCHEMBL16484985 0.96 KDM4E (0.38) KDM4EATML3MBTL1MEN1ALDH1A1
SCHEMBL16484989 0.96 KDM4E (0.38) KDM4EATML3MBTL1MEN1ALDH1A1
SCHEMBL16483872 0.96 KDM4E (0.38) KDM4EATML3MBTL1MEN1ALDH1A1
SCHEMBL16483911 0.96 KDM4E (0.38) KDM4EATML3MBTL1MEN1ALDH1A1
SCHEMBL16483873 0.95 KDM4E (0.39) KDM4EATML3MBTL1MEN1ALDH1A1
SCHEMBL16483881 0.95 KDM4E (0.39) KDM4EATML3MBTL1MEN1ALDH1A1
SCHEMBL16483814 0.95 KDM4E (0.38) KDM4EATML3MBTL1MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9960364-B2 Ladder compound, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 — — US disclosed
US-9960364-B2 Ladder compound, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 — — US disclosed
US-20150270496-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMIITSU KOSAN CO., LTD. (JP) 2015-09-24 — — US disclosed
US-20150270496-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMIITSU KOSAN CO., LTD. (JP) 2015-09-24 — — US disclosed
WO-2014057684-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 出光興産株式会社 (JP) 2014-04-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150270496-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME YBX1, ATXN2L, ATXN2 KDM4E 2405/4885ATM 3393/4885L3MBTL1 106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.