Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483423 | 0.92 | TNF (0.39) | TNFDYRK1ACYP11B1CYP11B2CYP17A1 | |
| SCHEMBL16484912 | 0.89 | TNF (0.41) | TNFDYRK1AKCNH2CYP11B1CYP11B2 | |
| SCHEMBL16484857 | 0.87 | TNF (0.39) | TNFDYRK1AKCNH2CYP11B1CYP11B2 | |
| SCHEMBL16484935 | 0.87 | TNF (0.42) | TNFDYRK1A | |
| SCHEMBL16483433 | 0.85 | TNF (0.40) | TNFDYRK1AKCNH2CYP11B1CYP11B2 | |
| SCHEMBL16484858 | 0.85 | TNF (0.36) | TNFDYRK1AKCNH2CYP11B1CYP11B2 | |
| SCHEMBL16484887 | 0.84 | TNF (0.34) | TNFDYRK1AKCNH2 | |
| SCHEMBL16484886 | 0.84 | TNF (0.35) | TNFDYRK1AKCNH2CYP11B1CYP11B2 | |
| SCHEMBL16484883 | 0.84 | TNF (0.43) | TNFDYRK1AKCNH2CYP11B1CYP11B2 | |
| SCHEMBL16483167 | 0.83 | TNF (0.37) | TNFDYRK1ACYP17A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |