Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 3/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483456 | 0.93 | TNF (0.36) | TNFALDH1A1NPSR1MEN1HSP90AA1 | |
| SCHEMBL16484886 | 0.89 | TNF (0.35) | TNFALDH1A1NPSR1DYRK1AMEN1 | |
| SCHEMBL16484912 | 0.88 | TNF (0.41) | TNFDYRK1AMEN1HSP90AA1MAPT | |
| SCHEMBL16484857 | 0.86 | TNF (0.39) | TNFDYRK1AKMT2ACDK4CDK6 | |
| SCHEMBL16484935 | 0.86 | TNF (0.42) | TNFALDH1A1DYRK1AMEN1HSP90AA1 | |
| SCHEMBL16484882 | 0.84 | TNF (0.36) | TNFDYRK1AKCNH2 | |
| SCHEMBL16483433 | 0.84 | TNF (0.40) | TNFDYRK1AMEN1HSP90AA1MAPT | |
| SCHEMBL16483555 | 0.83 | TNF (0.36) | TNFALDH1A1DYRK1ACDK4CDK6 | |
| SCHEMBL16483511 | 0.83 | TNF (0.38) | TNFALDH1A1NPSR1MEN1HSP90AA1 | |
| SCHEMBL16483167 | 0.82 | TNF (0.37) | TNFDYRK1AMEN1HSP90AA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |