Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30582710 | 0.91 | CA1 (0.48) | CA1CA2MEN1GAAKMT2A | |
| SCHEMBL29714777 | 0.90 | CA1 (0.47) | CA1CA2MEN1GAAKMT2A | |
| SCHEMBL16862479 | 0.88 | MEN1 (0.53) | CA1CA2MEN1GAAKMT2A | |
| SCHEMBL19776667 | 0.88 | MEN1 (0.53) | CA1CA2MEN1GAAKMT2A | |
| SCHEMBL14938898 | 0.88 | MEN1 (0.53) | CA1CA2MEN1GAAKMT2A | |
| SCHEMBL14938896 | 0.88 | MEN1 (0.53) | CA1CA2MEN1GAAKMT2A | |
| SCHEMBL24642514 | 0.86 | CA1 (0.49) | CA1CA2MEN1GAAKMT2A | |
| SCHEMBL22750240 | 0.85 | CTSS (0.53) | CA1CA2MEN1GAAKMT2A | |
| SCHEMBL22750241 | 0.85 | CTSS (0.53) | CA1CA2MEN1GAAKMT2A | |
| SCHEMBL26153776 | 0.84 | MEN1 (0.47) | CA1CA2MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057687-A1 | ANTIBODY-DRUG CONJUGATE | 第一三共株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |