Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166670 | 0.86 | NPC1 (0.51) | NPC1HPGDRAB9ASMN1; SMN2GRM5 | |
| SCHEMBL164349 | 0.78 | NOTUM (0.42) | POLBCASP3KDM4EMAPTNPC1 | |
| SCHEMBL28806785 | 0.75 | DPP4 (0.35) | POLBTDP1CASP3KMT2AKDM4E | |
| SCHEMBL163726 | 0.73 | PTGS1 (0.48) | POLBTDP1CASP3KMT2AKDM4E | |
| SCHEMBL29072516 | 0.71 | NPC1 (0.71) | CASP3KDM4EMAPTNPC1ALDH1A1 | |
| SCHEMBL16040665 | 0.70 | FLT3 (0.50) | CASP3KDM4EMAPTNPC1ALDH1A1 | |
| SCHEMBL161689 | 0.70 | KMT2A (0.43) | TDP1KMT2AKDM4EMAPTNPC1 | |
| SCHEMBL2528356 | 0.69 | NPC1 (0.57) | CASP3KMT2AKDM4EMAPTNPC1 | |
| SCHEMBL2611134 | 0.66 | KMT2A (0.54) | KMT2AKDM4EMAPTNPC1ALDH1A1 | |
| SCHEMBL28586484 | 0.66 | TDP1 (0.37) | POLBTDP1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611786-B1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2019-06-12 | — | — | EP | claimed |
| US-9907306-B2 | Compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2018-03-06 | — | — | US | claimed |
| US-20160227780-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2016-08-11 | — | — | US | claimed |
| US-9339035-B2 | Compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2016-05-17 | — | — | US | claimed |
| US-20130303368-A1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2013-11-14 | — | — | US | claimed |
| EP-2611786-B1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2019-06-12 | — | — | EP | disclosed |
| US-9907306-B2 | Compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2018-03-06 | — | — | US | disclosed |
| US-20160227780-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2016-08-11 | — | — | US | disclosed |
| US-9339035-B2 | Compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2016-05-17 | — | — | US | disclosed |
| US-20130303368-A1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2013-11-14 | — | — | US | disclosed |
| CN-103221397-A | Novel compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC | 2013-07-24 | — | — | CN | disclosed |
| EP-2611786-A1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | Monsanto Technology LLC (US) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012030887-A1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | DIVERGENCE, INC. (US) | 2012-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303368-A1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | PTMS, TUBA3C, TUBA1C | POLB 4277/4885TDP1 3214/4885CASP3 270/4885 |
| US-20160227780-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | PTMS, TUBA3C, TUBA1C | POLB 3973/4885TDP1 2738/4885CASP3 240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.