Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL164662 | 0.86 | GRM5 (0.55) | PTGS1F2GRM5MAPTNPC1 | |
| SCHEMBL165062 | 0.79 | ANO1 (0.42) | PTGS1CYP1A2CYP2C9GRM5MAPT | |
| SCHEMBL27930851 | 0.76 | ADORA3 (0.41) | PTGS1CYP1A2CYP2C19CYP2C9F2 | |
| SCHEMBL29072516 | 0.74 | NPC1 (0.71) | GRM5MAPTNPC1RAB9AKDM4E | |
| SCHEMBL164860 | 0.73 | POLB (0.47) | CYP1A2CYP2C19CYP2C9F2GRM5 | |
| SCHEMBL164664 | 0.70 | NPC1 (0.50) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL4700569 | 0.70 | GRM5 (0.72) | GRM5 | |
| SCHEMBL8578631 | 0.70 | RAB9A (0.81) | GRM5MAPTNPC1RAB9APOLB | |
| SCHEMBL16039655 | 0.70 | FLT3 (0.55) | PTGS1CYP1A2CYP2C19MAPTNPC1 | |
| SCHEMBL2528356 | 0.69 | NPC1 (0.57) | GRM5MAPTNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611786-B1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2019-06-12 | — | — | EP | claimed |
| US-9907306-B2 | Compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2018-03-06 | — | — | US | claimed |
| US-20160227780-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2016-08-11 | — | — | US | claimed |
| US-9339035-B2 | Compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2016-05-17 | — | — | US | claimed |
| US-20130303368-A1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2013-11-14 | — | — | US | claimed |
| EP-2611786-B1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2019-06-12 | — | — | EP | disclosed |
| US-9907306-B2 | Compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2018-03-06 | — | — | US | disclosed |
| US-20160227780-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2016-08-11 | — | — | US | disclosed |
| US-9339035-B2 | Compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC (US) | 2016-05-17 | — | — | US | disclosed |
| US-20130303368-A1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | MONSANTO TECHNOLOGY LLC (US) | 2013-11-14 | — | — | US | disclosed |
| CN-103221397-A | Novel compositions and methods for controlling nematode pests | MONSANTO TECHNOLOGY LLC | 2013-07-24 | — | — | CN | disclosed |
| EP-2611786-A1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | Monsanto Technology LLC (US) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012030887-A1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | DIVERGENCE, INC. (US) | 2012-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303368-A1 | NEW COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | PTMS, TUBA3C, TUBA1C | PTGS1 2687/4885CYP1A2 623/4885CYP2C19 1893/4885 |
| US-20160227780-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODE PESTS | PTMS, TUBA3C, TUBA1C | PTGS1 2863/4885CYP1A2 481/4885CYP2C19 1810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.