Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31260402 | 0.80 | PI4KA (0.43) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL9038851 | 0.74 | PARP1 (0.57) | PARP1TLR8TLR7 | |
| SCHEMBL3922879 | 0.72 | PI4KA (0.40) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL31260407 | 0.72 | PI4KA (0.40) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL29871746 | 0.72 | TLR7 (0.48) | PI4KAPI4K2BPI4K2API4KBTLR8 | |
| SCHEMBL30663229 | 0.71 | PI4KA (0.40) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL29109863 | 0.71 | PI4KA (0.40) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL32675794 | 0.70 | PI4KA (0.39) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL30663228 | 0.70 | PI4KA (0.39) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL29840892 | 0.70 | TLR8 (0.41) | PI4KAPI4K2BPI4K2API4KBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015023958-A1 | TOLL-LIKE RECEPTOR AGONISTS | THE UNIVERSITY OF KANSAS (US) | 2015-02-19 | — | — | WO | disclosed |