Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29109863 | 1.00 | PI4KA (0.40) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL29840892 | 0.77 | TLR8 (0.41) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL30663228 | 0.77 | PI4KA (0.39) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL32675794 | 0.77 | PI4KA (0.39) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| Hydrochloric Acid SCHEMBL29840678 | 0.76 | TLR8 (0.40) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL32675775 | 0.71 | NPY5R (0.41) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL16486305 | 0.71 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL29840920 | 0.69 | PI4KA (0.35) | PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL32675782 | 0.69 | PI4KA (0.39) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL32675790 | 0.68 | PI4KA (0.36) | PI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288438-B1 | DERIVATIVES OF IMIDAZO[4,5-D]PYRIDAZINE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI SA (FR) | 2026-02-18 | — | — | EP | claimed |
| CN-117098761-A | Imidazo [4,5-d ] pyridazine derivatives, preparation thereof and therapeutic use thereof | 赛诺菲 | 2023-11-21 | — | — | CN | claimed |
| US-12583861-B2 | Derivatives of imidazo[4,5-d]pyridazine, their preparation and their therapeutic application | SANOFI (FR) | 2026-03-24 | — | — | US | disclosed |
| US-20240158401-A1 | DERIVATIVES OF IMIDAZO[4,5-d]PYRIDAZINE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2024-05-16 | — | — | US | disclosed |
| CN-117098761-A | Imidazo [4,5-d ] pyridazine derivatives, preparation thereof and therapeutic use thereof | 赛诺菲 | 2023-11-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12583861-B2 | Derivatives of imidazo[4,5-d]pyridazine, their preparation and their therapeutic application | TLR7, TLR8, TLR6 | PI4KA 1721/4885PI4K2B 1955/4885PI4K2A 1910/4885 |
| US-20240158401-A1 | DERIVATIVES OF IMIDAZO[4,5-d]PYRIDAZINE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | TLR7, TLR8, TLR6 | PI4KA 2368/4885PI4K2B 2718/4885PI4K2A 2638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.