Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | STAT1 | P42224 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16487362 | 0.83 | ADORA1 (0.62) | KDM4EHTTCYP2C9ADORA1APP | |
| SCHEMBL9181006 | 0.72 | MAPK1 (0.60) | KDM4EMAPK1HTTSMN1; SMN2STAT1 | |
| SCHEMBL25434690 | 0.72 | RCE1 (0.48) | KDM4EMAPK1HTTSMN1; SMN2CYP2C9 | |
| SCHEMBL10585221 | 0.72 | SMN1; SMN2 (0.59) | SMN1; SMN2CYP2C9MAPTCYP1A2CYP2C19 | |
| SCHEMBL12831446 | 0.72 | KDM4E (1.00) | KDM4EMAPK1HTTSMN1; SMN2STAT1 | |
| SCHEMBL14978997 | 0.72 | KDM4A (0.45) | KDM4EMAPK1HTTSMN1; SMN2CYP2C9 | |
| SCHEMBL253744 | 0.71 | KDM4E (0.60) | KDM4EMAPK1HTTSMN1; SMN2STAT1 | |
| SCHEMBL18136489 | 0.71 | SMN1; SMN2 (0.46) | KDM4EMAPK1HTTSMN1; SMN2MAPT | |
| SCHEMBL15262543 | 0.71 | TP53 (0.72) | KDM4EMAPK1HTTADORA1APP | |
| SCHEMBL12376827 | 0.71 | KDM4E (0.47) | KDM4EMAPK1HTTSMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015022284-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2015-02-19 | — | — | WO | disclosed |