Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | APP | P05067 | 3/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16487384 | 0.87 | MAPT (0.58) | ADORA1ADORA2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL16487460 | 0.86 | MAPT (0.59) | ADORA1KDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL16486682 | 0.83 | KDM4E (0.56) | ADORA1ADORA2AKDM4EALDH1A1HPGD | |
| SCHEMBL22920713 | 0.82 | PDE4D (0.58) | ADORA1ADORA2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL14668518 | 0.76 | KDM4E (1.00) | ADORA1ADORA2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL28355260 | 0.76 | ALDH1A1 (0.72) | ADORA1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL11391965 | 0.76 | MAPK1 (0.70) | KDM4EALDH1A1HSD17B10HPGDALOX12 | |
| SCHEMBL25077867 | 0.75 | ALDH1A1 (0.62) | ADORA1ADORA2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL28728715 | 0.75 | NPC1 (0.62) | ADORA1ADORA2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL13741611 | 0.75 | KDM4E (0.64) | ADORA1ADORA2AKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015022284-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2015-02-19 | — | — | WO | disclosed |