Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9288039 | 0.83 | KCNN4 (0.42) | KCNN4KIF11KCNH2TAAR1KDM4E | |
| Hydrochloric Acid SCHEMBL7409176 | 0.82 | KCNN4 (0.41) | KCNN4KIF11KCNH2TAAR1KDM4E | |
| SCHEMBL28191621 | 0.79 | TAAR1 (0.50) | KCNN4KIF11KCNH2TAAR1MAPK1 | |
| SCHEMBL28982645 | 0.78 | CES1 (0.42) | KCNN4KIF11MEN1KMT2ALMNA | |
| SCHEMBL3205214 | 0.78 | KCNN4 (0.41) | KCNN4KIF11KCNH2TAAR1KDM4E | |
| SCHEMBL157809 | 0.76 | KCNN4 (0.48) | KCNN4KIF11TAAR1CYP1A2CYP2D6 | |
| SCHEMBL9187550 | 0.75 | KCNN4 (0.41) | KCNN4KIF11KCNH2TAAR1KDM4E | |
| SCHEMBL9756593 | 0.74 | KCNN4 (0.46) | KCNN4KIF11TAAR1CYP1A2CYP2D6 | |
| SCHEMBL453502 | 0.74 | KCNN4 (0.46) | KCNN4KIF11TAAR1CYP1A2CYP2D6 | |
| Bromide SCHEMBL10687152 | 0.74 | KCNN4 (0.46) | KCNN4KIF11TAAR1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015022631-A1 | SUBSTITUTED BIPHENYL COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN LIMITED (IN) | 2015-02-19 | — | — | WO | disclosed |