SCHEMBL157809

SCHEMBL157809

CCCC(N)(c1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.48
TAAR1 Q96RJ0 2/20 0.44
KIF11 P52732 4/20 0.41
SLC6A2 P23975 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
MAPK1 P28482 1/20 0.37
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL10687152 0.98 KCNN4 (0.46) KCNN4TAAR1KIF11SLC6A2CYP1A2
SCHEMBL10384482 0.86 KIF11 (0.45) KCNN4TAAR1KIF11ESR1ESR2
SCHEMBL6249559 0.84 PTPN1 (0.41) KCNN4KIF11
SCHEMBL3402192 0.84 KCNN4 (0.42) KCNN4TAAR1KIF11
SCHEMBL9756593 0.83 KCNN4 (0.46) KCNN4TAAR1KIF11SLC6A2CYP1A2
SCHEMBL453502 0.83 KCNN4 (0.46) KCNN4TAAR1KIF11SLC6A2CYP1A2
SCHEMBL10589325 0.82 SCN5A (0.42) KCNN4KIF11
SCHEMBL11757213 0.82 SCN5A (0.42) KCNN4KIF11
SCHEMBL11751250 0.82 SCN5A (0.42) KCNN4KIF11
SCHEMBL2836376 0.82 SCN5A (0.42) KCNN4KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 556 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007062862-A2 USE OF CALMODULIN INHIBITORS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS LUDWIG MAXIMILIANS UNIVERSITÄT MÜNCHEN (DE) 2007-06-07 WO claimed
US-20030064929-A1 Modulating body/cranial hair growth DURANTON ALBERT (FR) 2003-04-03 US claimed
EP-0648488-B1 Method to alter hairgrowth and compositions therefor OREAL (FR) 2000-11-29 EP claimed
US-5928654-A Modulating body/cranial hair growth with lipoxygenase/cyclooxygenase inhibitors SOCIETE L'OREAL S.A. (FR) 1999-07-27 US claimed
EP-0800815-A2 Use of at least one lypoxygenase inhibitor and at least one cyclo-oxygenase inhibitor to alter hair growth L'OREAL (FR) 1997-10-15 EP claimed
EP-0648488-A1 Method to alter hairgrowth and compositions therefor L'OREAL (FR) 1995-04-19 EP claimed
EP-0428754-B1 HAIR GROWTH STIMULANT SHISEIDO CO LTD (JP) 1994-05-25 EP claimed
EP-0428754-A1 HAIR GROWTH STIMULANT SHISEIDO COMPANY LIMITED (JP) 1991-05-29 EP claimed
EP-0168626-B1 COMPOSITION FOR THE MANUFACTURE OF A MEDICAMENT FOR THE THERAPEUTIC TREATMENT OF TRAUMA OF THE SKIN BAR-ILAN UNIVERSITY (IL) 1990-09-12 EP claimed
US-4654323-A BLOCKING AGENT FOR CALCIUM CALMODULIN COMPLEX BAR ILAN UNIVERSITY (IL) 1987-03-31 US claimed
EP-0168626-A1 Composition for the manufacture of a medicament for the therapeutic treatment of trauma of the skin BAR-ILAN UNIVERSITY (IL) 1986-01-22 EP claimed
EP-0082203-A1 USE OF CALMODULIN BINDING DRUGS IN UTERUS TO PREVENT PREGNANCY THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1983-06-29 EP claimed
US-4377577-A Use of psychoactive drugs in uterus to prevent pregnancy UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1983-03-22 US claimed
WO-1983000086-A1 USE OF CALMODULIN BINDING DRUGS IN UTERUS TO PREVENT PREGNANCY UNIV GEORGIA RES FOUND (US) 1983-01-20 WO claimed
EP-0053108-A1 VAGINAL CONTRACEPTIVES COMPRISING PSYCHOACTIVE DRUGS THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1982-06-09 EP claimed
WO-1981003421-A1 USE OF PSYCHOACTIVE DRUGS AS VAGINAL CONTRACEPTIVES UNIV GEORGIA (US) 1981-12-10 WO claimed
JP-54084578-A None JP disclosed
CN-119365447-A Process for preparing substantially nitrosamine-free, peroxide-free, substantially colorless amine oxide 巴斯夫欧洲公司 2025-01-24 CN disclosed
JP-S5484578-A NOVEL PREPARATION OF DIPHENYLBUTYLAMINE DERIVATIVE SUMITOMO CHEM CO LTD 1979-07-05 JP disclosed
US-4034011-A 1,1-Diphenyl-4-(substituted-amino)butanes ELI LILLY AND COMPANY (US) 1977-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030064929-A1 Modulating body/cranial hair growth ALOX15B, ALOX12, ALOX5 KCNN4 3541/4885TAAR1 1922/4885KIF11 4542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.