SCHEMBL16487294

SCHEMBL16487294

CCO[Si](C)(C)c1cccc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
ALDH1A1 P00352 3/20 0.38
HTR1B P28222 3/20 0.38
CYP2A6 P11509 2/20 0.38
CDC25B P30305 2/20 0.37
TSHR P16473 2/20 0.36
ENPP1 P22413 1/20 0.35
S1PR1 P21453 1/20 0.35
S1PR3 Q99500 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
ELANE P08246 1/20 0.35
CDC25A P30304 1/20 0.35
CDC25C P30307 1/20 0.35
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9651521 0.85 HPGD (0.39) HPGDKDM4ELMNAALDH1A1HTR1B
SCHEMBL6850272 0.85 HPGD (0.39) HPGDKDM4ELMNAALDH1A1HTR1B
SCHEMBL29444236 0.85 HPGD (0.39) HPGDKDM4ELMNAALDH1A1HTR1B
SCHEMBL106903 0.83 HPGD (0.40) HPGDKDM4ELMNAALDH1A1HTR1B
SCHEMBL20483655 0.83 HPGD (0.40) HPGDKDM4ELMNAALDH1A1HTR1B
SCHEMBL29404268 0.83 HPGD (0.40) HPGDKDM4ELMNAALDH1A1HTR1B
SCHEMBL5050571 0.83 HPGD (0.40) HPGDKDM4ELMNAALDH1A1HTR1B
SCHEMBL29859741 0.83 HPGD (0.40) HPGDKDM4ELMNAALDH1A1HTR1B
SCHEMBL6750035 0.83 NQO1 (0.34) HPGDKDM4ELMNAALDH1A1CYP2A6
SCHEMBL2961136 0.82 ALDH1A1 (0.32) HPGDKDM4EALDH1A1TSHRELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107076894-B Infrared shielding composition, cured film, and solid-state imaging device JSR株式会社 2020-01-31 CN disclosed
CN-105593234-B Novel organopolysiloxane, the surface conditioning agent comprising it, the resin combination comprising it and their gel-like product or cured product 道康宁东丽株式会社 2018-10-26 CN disclosed
CN-107076894-A Infrared shielding composition, cured film, and solid-state imaging device JSR株式会社 2017-08-18 CN disclosed
CN-105593234-A Novel organopolysiloxane, surface treatment agent comprising the same, resin composition comprising the same, and gelatinous product or cured product thereof DOW CORNING TORAY CO LTD 2016-05-18 CN disclosed
WO-2015023001-A1 NOVEL ORGANOPOLYSILOXANE, SURFACE TREATMENT AGENT COMPRISING THE SAME, RESIN COMPOSITION COMPRISING THE SAME, AND GELATINOUS PRODUCT OR CURED PRODUCT THEREOF DOW CORNING TORAY CO., LTD. (JP) 2015-02-19 WO disclosed