SCHEMBL16487332

SCHEMBL16487332

CC(c1ccc2ccccc2c1)[Si](C)(C)Cl

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
UGT2B7 P16662 1/20 0.55
MMP9 P14780 1/20 0.45
ADRA2A P08913 3/20 0.44
ADRA2B P18089 3/20 0.44
ADRA2C P18825 3/20 0.44
CYP2D6 P10635 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CYP1A2 P05177 2/20 0.44
TSHR P16473 1/20 0.44
HIF1A Q16665 1/20 0.44
ATM Q13315 1/20 0.43
AOC3 Q16853 2/20 0.41
CYP2A6 P11509 1/20 0.41
CYP3A4 P08684 2/20 0.41
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41
SLC6A3 Q01959 2/20 0.41
KCNH2 Q12809 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15672882 0.77 UGT2B7 (0.55) UGT2B7MMP9ADRA2AADRA2BADRA2C
SCHEMBL30928206 0.77 UGT2B7 (0.71) UGT2B7MMP9ADRA2AADRA2BADRA2C
SCHEMBL29555341 0.77 UGT2B7 (0.71) UGT2B7MMP9ADRA2AADRA2BADRA2C
Naphthalene SCHEMBL29078859 0.77 UGT2B7 (0.71) UGT2B7MMP9ADRA2AADRA2BADRA2C
Naphthalene SCHEMBL9636781 0.77 UGT2B7 (0.71) UGT2B7MMP9ADRA2AADRA2BADRA2C
SCHEMBL9179436 0.77 UGT2B7 (0.71) UGT2B7MMP9ADRA2AADRA2BADRA2C
SCHEMBL599956 0.77 UGT2B7 (0.71) UGT2B7MMP9ADRA2AADRA2BADRA2C
SCHEMBL28668334 0.76 UGT2B7 (0.53) UGT2B7MMP9ADRA2AADRA2BADRA2C
SCHEMBL6191864 0.75 UGT2B7 (0.63) UGT2B7MMP9ADRA2AADRA2BADRA2C
SCHEMBL29817405 0.75 UGT2B7 (0.63) UGT2B7MMP9ADRA2AADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105593234-B Novel organopolysiloxane, the surface conditioning agent comprising it, the resin combination comprising it and their gel-like product or cured product 道康宁东丽株式会社 2018-10-26 CN disclosed
WO-2015023001-A1 NOVEL ORGANOPOLYSILOXANE, SURFACE TREATMENT AGENT COMPRISING THE SAME, RESIN COMPOSITION COMPRISING THE SAME, AND GELATINOUS PRODUCT OR CURED PRODUCT THEREOF DOW CORNING TORAY CO., LTD. (JP) 2015-02-19 WO disclosed