SCHEMBL28668334

SCHEMBL28668334

CC[Si](CC)(CC)C(C)c1ccc2ccccc2c1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
UGT2B7 P16662 1/20 0.53
ADRA2A P08913 2/20 0.46
ADRA2B P18089 2/20 0.46
ADRA2C P18825 2/20 0.46
CYP2D6 P10635 3/20 0.46
CYP1A2 P05177 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
TSHR P16473 1/20 0.46
HIF1A Q16665 1/20 0.46
AOC3 Q16853 2/20 0.44
MMP9 P14780 1/20 0.44
CYP2A6 P11509 1/20 0.42
ATM Q13315 1/20 0.42
SLC6A2 P23975 3/20 0.41
SLC6A4 P31645 3/20 0.41
SLC6A3 Q01959 3/20 0.41
KCNH2 Q12809 3/20 0.41
CYP3A4 P08684 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8140789 0.79 UGT2B7 (0.50) UGT2B7ADRA2AADRA2BADRA2CCYP2D6
SCHEMBL15672882 0.76 UGT2B7 (0.55) UGT2B7ADRA2AADRA2BADRA2CCYP2D6
SCHEMBL16487332 0.76 UGT2B7 (0.55) UGT2B7ADRA2AADRA2BADRA2CCYP2D6
SCHEMBL599956 0.75 UGT2B7 (0.71) UGT2B7ADRA2AADRA2BADRA2CCYP2D6
Naphthalene SCHEMBL9636781 0.75 UGT2B7 (0.71) UGT2B7ADRA2AADRA2BADRA2CCYP2D6
SCHEMBL30928206 0.75 UGT2B7 (0.71) UGT2B7ADRA2AADRA2BADRA2CCYP2D6
SCHEMBL29555341 0.75 UGT2B7 (0.71) UGT2B7ADRA2AADRA2BADRA2CCYP2D6
SCHEMBL9179436 0.75 UGT2B7 (0.71) UGT2B7ADRA2AADRA2BADRA2CCYP2D6
Naphthalene SCHEMBL29078859 0.75 UGT2B7 (0.71) UGT2B7ADRA2AADRA2BADRA2CCYP2D6
SCHEMBL5401290 0.75 UGT2B7 (0.59) UGT2B7CYP2D6CYP1A2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113717209-A Synthesis method of alkyl silicon compound 南通大学 2021-11-30 CN disclosed