Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13041525 | 0.92 | KDM4E (0.46) | KDM4ERAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL13041400 | 0.77 | RAB9A (0.40) | KDM4ERAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL2762937 | 0.72 | HRH3 (0.41) | KDM4ERAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL10237969 | 0.70 | SMN1; SMN2 (0.46) | KDM4ERAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL13058537 | 0.70 | KDM4E (0.43) | KDM4ERAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL13041556 | 0.69 | GAA (0.37) | KDM4ERAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL13041538 | 0.66 | TARBP2 (0.42) | KDM4ERAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL13041398 | 0.66 | MAPT (0.38) | KDM4ERAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL13041406 | 0.65 | NPC1 (0.36) | KDM4ENPC1MAPT | |
| SCHEMBL13041486 | 0.65 | PPARA (0.31) | KDM4EGAAALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8956999-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2015-02-17 | — | — | US | disclosed |