Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGT | O15294 | 9/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16487587 | 0.90 | CYP3A4 (0.65) | OGTCYP3A4CYP2D6CYP2C9POLB | |
| SCHEMBL4544776 | 0.88 | OGT (0.88) | OGTCYP3A4CYP2D6POLBGAA | |
| SCHEMBL16487640 | 0.86 | OGT (0.84) | OGTCYP3A4CYP2D6POLBGAA | |
| SCHEMBL10131963 | 0.86 | OGT (1.00) | OGTPOLBGAAMAPTTDP1 | |
| SCHEMBL16487949 | 0.84 | OGT (0.80) | OGTPOLBGAAMAPTTDP1 | |
| SCHEMBL16488012 | 0.84 | OGT (0.80) | OGTPOLBGAAMAPTTDP1 | |
| SCHEMBL16488019 | 0.82 | OGT (0.78) | OGTPOLBGAAMAPTTDP1 | |
| SCHEMBL16487615 | 0.82 | OGT (0.73) | OGTPOLBGAAMAPTTDP1 | |
| SCHEMBL16488014 | 0.82 | OGT (0.72) | OGTPOLBGAAMAPTTDP1 | |
| SCHEMBL16487964 | 0.82 | OGT (0.75) | OGTCYP3A4CYP2D6POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8957075-B2 | O-GlcNAc transferase inhibitors and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-02-17 | — | — | US | disclosed |
| US-8957075-B2 | O-GlcNAc transferase inhibitors and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-02-17 | — | — | US | disclosed |