Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18257489 | 1.00 | GDA (0.34) | GDAKMT2AADORA3ALDH1A1KDM4E | |
| SCHEMBL15325115 | 1.00 | GDA (0.34) | GDAKMT2AADORA3ALDH1A1KDM4E | |
| SCHEMBL16488194 | 0.87 | KMT2A (0.36) | GDAKMT2AADORA3ALDH1A1KDM4E | |
| SCHEMBL18658555 | 0.87 | KMT2A (0.36) | GDAKMT2AADORA3ALDH1A1KDM4E | |
| SCHEMBL16639442 | 0.83 | ADORA3 (0.41) | GDAKMT2AADORA3ALDH1A1KDM4E | |
| SCHEMBL18658580 | 0.81 | GDA (0.39) | GDAKMT2AADORA3ALDH1A1KDM4E | |
| SCHEMBL16466807 | 0.79 | KMT2A (0.36) | GDAKMT2AADORA3ALDH1A1KDM4E | |
| SCHEMBL18658563 | 0.76 | ATM (0.35) | KMT2ADPP4SMN1; SMN2 | |
| SCHEMBL4069624 | 0.72 | POLB (0.48) | GDAKMT2AADORA3ALDH1A1KDM4E | |
| SCHEMBL15325124 | 0.71 | GDA (0.43) | GDAKMT2AADORA3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2837629-A1 | METHOD FOR SYNTHESIZING SAPROPTERIN DIHYDROCHLORIDE | Asymchem Laboratories (Tianjin) Co., Ltd (CN) | 2015-02-18 | — | — | EP | disclosed |