Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3655934 | 0.90 | APP (0.40) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3656212 | 0.86 | APP (0.44) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3663037 | 0.80 | APP (0.42) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8031700 | 0.80 | APP (0.49) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3658526 | 0.79 | APP (0.41) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4376035 | 0.79 | APP (0.38) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL16284090 | 0.78 | OPRM1 (0.40) | — | |
| SCHEMBL4381300 | 0.78 | APP (0.44) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4379440 | 0.78 | APP (0.49) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3659542 | 0.77 | APP (0.49) | APPPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234954-B1 | TETRASUBSTITUTED BENZENES | ENVIVO PHARMACEUTICALS INC (US) | 2015-02-18 | — | — | EP | disclosed |