Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14839480 | 0.93 | CYP1A2 (0.45) | CYP1A2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14839483 | 0.93 | CYP1A2 (0.45) | CYP1A2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14839506 | 0.91 | TRPV1 (0.47) | CYP1A2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14839504 | 0.91 | TRPV1 (0.43) | CYP1A2NPC1RAB9ASMN1; SMN2TRPV1 | |
| SCHEMBL14839612 | 0.89 | TRPV1 (0.51) | CYP1A2ALDH1A1MAPTTRPV1LMNA | |
| SCHEMBL14832109 | 0.89 | TRPV1 (0.51) | CYP1A2ALDH1A1MAPTTRPV1LMNA | |
| SCHEMBL14832450 | 0.89 | TRPV1 (0.51) | CYP1A2ALDH1A1MAPTTRPV1LMNA | |
| SCHEMBL14230569 | 0.79 | CYP1A2 (0.52) | CYP1A2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29898471 | 0.79 | CYP1A2 (0.47) | CYP1A2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14839478 | 0.79 | KDM4E (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2775996-B1 | USE OF PROPANOL AND PROPENOL DERIVATIVES AS ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2018-02-28 | — | — | EP | disclosed |
| US-20150051295-A1 | USE OF PROPANOL AND PROPENOL DERIVATIVES AS ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2015-02-19 | — | — | US | disclosed |
| US-20150051295-A1 | USE OF PROPANOL AND PROPENOL DERIVATIVES AS ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051295-A1 | USE OF PROPANOL AND PROPENOL DERIVATIVES AS ANTIOXIDANTS | GPX4, EBP, CAT | CYP1A2 292/4885NPC1 2341/4885RAB9A 4513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.