Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.42 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.42 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.42 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAPDH | P04406 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19036047 | 0.90 | PTPN1 (0.42) | POLBMEN1USP2KMT2AALDH1A1 | |
| SCHEMBL25584339 | 0.89 | POLB (0.52) | POLBMEN1USP2KMT2AALDH1A1 | |
| SCHEMBL19263956 | 0.89 | POLB (0.52) | POLBMEN1USP2KMT2AALDH1A1 | |
| SCHEMBL16489270 | 0.87 | LGALS9 (0.43) | POLBMEN1USP2KMT2AALDH1A1 | |
| SCHEMBL5707687 | 0.87 | USP2 (0.55) | POLBMEN1USP2KMT2AALDH1A1 | |
| SCHEMBL2493929 | 0.87 | USP2 (0.55) | POLBMEN1USP2KMT2AALDH1A1 | |
| SCHEMBL11061066 | 0.87 | USP2 (0.55) | POLBMEN1USP2KMT2AALDH1A1 | |
| SCHEMBL14274463 | 0.87 | USP2 (0.55) | POLBMEN1USP2KMT2AALDH1A1 | |
| SCHEMBL11726595 | 0.87 | USP2 (0.55) | POLBMEN1USP2KMT2AALDH1A1 | |
| SCHEMBL26801670 | 0.87 | USP2 (0.55) | POLBMEN1USP2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150050367-A1 | TIMOSAPONIN COMPOUNDS | GOLDPORP PHARMA LIMITED (HK) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150050367-A1 | TIMOSAPONIN COMPOUNDS | APP, IAPP, BACE1 | POLB 3050/4885MEN1 1058/4885USP2 4673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.