Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 18/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 17/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 17/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 11/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 9/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 8/20 | 0.50 |
| ▸ | CASP7 | P55210 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16489696 | 0.86 | BRD4 (0.61) | BRD4 | |
| SCHEMBL16489642 | 0.84 | BRD4 (0.61) | BRD4 | |
| SCHEMBL16489607 | 0.82 | BRD4 (0.61) | BRD4 | |
| SCHEMBL16489707 | 0.81 | BRD4 (0.60) | BRD4CYP1A2ALDH1A1HSD17B10CYP2C9 | |
| SCHEMBL16489698 | 0.78 | BRD4 (0.62) | BRD4 | |
| SCHEMBL16489699 | 0.78 | BRD4 (0.54) | BRD4CYP1A2ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL16489671 | 0.77 | BRD4 (0.61) | BRD4 | |
| SCHEMBL16489697 | 0.76 | BRD4 (0.60) | BRD4 | |
| SCHEMBL16489654 | 0.76 | BRD4 (0.65) | BRD4 | |
| SCHEMBL16489653 | 0.76 | BRD4 (0.62) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296748-B2 | Pyridinones | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-03-29 | — | — | US | disclosed |
| US-20150246919-A1 | PYRIDINONES | BOEHRINGER INGELHEIM INT (DE) | 2015-09-03 | — | — | US | disclosed |
| US-20150051208-A1 | PYRIDINONES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051208-A1 | PYRIDINONES | MKI67, XDH, CDK6 | BRD4 1346/4885CYP1A2 203/4885ALDH1A1 545/4885 |
| US-20150246919-A1 | PYRIDINONES | MKI67, XDH, CDK6 | BRD4 1346/4885CYP1A2 203/4885ALDH1A1 545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.